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YU News

Vigodner Publishes Article in Biochemical and Biophysical Research Communications

vigodner_300 Margarita Vigodner

Dr. Margarita Vigodner, associate professor of biology at Stern College for Women, has co-authored a new paper, “Cross-talk between sumoylation and phosphorylation in mouse spermatocytes,” with Yuxuan Xiao, Benjamin Lucas and Elana Molcho, that has been accepted to Biochemical and Biophysical Research Communications.

In at least half of all cases of human infertility (one in every six couples who are trying to conceive), male spermatogenic failure is a major or contributing cause. Vigodner's work focuses on understanding a crucial step of spermatogenesis called meiosis, which is critical for normal fertility. This research will lead to a better understanding of possible causes of chromosome abnormalities and male infertility, and may lead to the development of novel safe contraceptives, thus improving human healthcare.

The research was led by Vigodner. Yuxuan Xiao and  Benjamin Lucas have been postdoctoral research associates  in her lab, and Elana Molcho is a recent Stern graduate who was trained in the laboratory as a member of the S. Daniel Abraham Honors Program.